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Scientists create a 'minimal' cell using just the genes needed to survive Let there be artificial life! Tiny lifeform created with just 473 'essential' genes could unlock the secrets of our existence Scientists have created a new artificial bacterial cell nicknamed Synthia 3.
0They did this by stripping down the bacterial genome to just 473 genesThese were the minimal genes found to be essential to maintain lifeIt could lead to pandora order new forms of customised synthetic life capable of cleaning up pollution, producing biofuels or pumping out vaccines on demandBy Fiona Macrae, Science Editor For The Daily MailThey then methodically inserted foreign genetic sequences into the genes of the bacteria to disrupt their function and determine which were necessary to the overall survival of the bacteria. This allowed them to gradually whittle away the genome until no more could be disrupted without the cell dying. They then used this to synthesis an artificial genome that they were able to insert it back into an empty bacterial cell. The minimal genome they produced lacks all the genes needed to modify DNA and a group of genes encoding lipoproteins. In contrast, almost all the genes involved in reading and expressing the genetic information in the genome as well as passing genetic information to future generations were retained. The scientists say this basic form of life may help them understand the function of every essential gene in a cell. However, jewelry stores that sell pandora charms the technology opens a Pandora's box of ethical problems. Critics of such synthetic biology research accuse scientists of playing God. There are also pandora gold pendant fears the technique could be abused to create the artificial biological weapon. Six years ago, Dr Ventor a 69 year old Vietnam War veteran and billionaire entrepreneur, made headlines around the world when he announced he had made artificial life for the first time. To do this, he read the DNA of Mycoplasma mycoides, a bug that usually infects goats. He then recreated the DNA, stitching it together from fragments of genetic code made from four bottles of chemicals. This DNA was then loaded into a bacterium from a different species. This bacterium read the DNA and sprang to life as an artificial bug he named affectionately named Synthia 1.0. Dr Venter, who was instrumental in the sequencing of the human genome, has now gone a step further. By a process of trial and error, he pandora watches australia has worked out which of the 900 odd genes in Synthia 1.0 are essential for life. This led to the creation of Synthia 3.0, which boasts the 473 genes needed to grow and reproduce. The human genome, by comparison has 24,000 genes. A normal Mycoplasma mycoides has just over 1,000 genes. If life is defined as the ability to grow and breed without help, it makes the bug the simplest living thing.
In theory Synthia 3.0, or a similar skeleton bug, could be accessorised with genes that could revolutionise healthcare and fuel production. Dr Venter, of the J, Craig Venter Institute in California, said some of the possibilities are still outwith the realms of human imagination.
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